PVP/VA Copolymer (Copovidone)
PVP/VA Copolymer (Copovidone)
PVP/VA Copolymer, known as Copovidone, is a versatile synthetic polymer widely utilized in the pharmaceutical and cosmetics industries. As a co-polymer of vinylpyrrolidone and vinyl acetate, Copovidone offers excellent film-forming, adhesion, and solubilizing properties. It is particularly valued in pharmaceutical formulations as a binder and pore-former in both tablets and transdermal systems, enhancing the bioavailability of drugs. In cosmetics, its application ranges from hair sprays and mousses to makeup, where it provides durable, flexible films and improves the texture and stability of products.
Product Details
01
Overview
PVP/VA Copolymer, commonly referred to as Copovidone, is a multifaceted synthetic copolymer that plays a pivotal role in both the pharmaceutical and cosmetic industries. Comprising varying ratios of N-Vinylpyrrolidone (NVP) to Vinyl Acetate (VA), this polymer is tailored to meet specific application needs, offering versatility in solubility and film-forming capabilities. It is uniquely soluble in a broad spectrum of organic solvents, making it highly adaptable for diverse formulations.
Available in powder form, as well as in aqueous and ethanol solutions, Copovidone caters to a wide range of product formulations. This copolymer is esteemed for its ability to form hard, glossy films that are easily removable with water, a characteristic particularly beneficial in the development of innovative pharmaceutical coatings and cosmetic products. The films created are not only aesthetically pleasing but also provide a protective barrier that enhances product stability and performance.
One of the standout attributes of PVP/VA Copolymer is its excellent compatibility with a plethora of plasticizers and modifiers. This compatibility allows for the creation of customized formulations that can meet the precise needs of manufacturers, offering flexibility in product design and functionality. Additionally, the hydrophilicity of Copovidone decreases in proportion to the amount of Vinyl Acetate present, a feature that can be strategically utilized to control the moisture sensitivity of the final product.
The adjustable ratio of NVP to VA in Copovidone formulations provides formulators with the ability to fine-tune the balance between solubility, film strength, and hydrophilicity, ensuring that the end products meet the desired specifications for a wide array of applications. From enhancing the bioavailability of drugs in pharmaceutical applications to improving the durability and finish of cosmetics, PVP/VA Copolymer stands out as a critical ingredient that brings innovation and quality to the forefront of product development.
02
Applications
The PVP/VA Copolymer, or Copovidone, finds its applications across a variety of fields, benefiting from its versatile properties and compatibility with other substances:
Pharmaceutical Coatings: Leveraging its film-forming capabilities, Copovidone is widely used in the pharmaceutical industry to create coatings for tablets and capsules. These coatings enhance the product’s appearance, protect the active ingredient, control release profiles, and improve swallowability.
Transdermal and Topical Medications: Its ability to form hard yet water-removable films makes it ideal for transdermal patches and topical creams. Copovidone helps in controlling drug release and increasing the adhesion of products to the skin without causing irritation.
Cosmetic Products: In cosmetics, Copovidone is utilized for its glossy finish and film-forming properties. It is found in hair styling products like gels and mousses, providing hold and shine while being easy to wash out. Additionally, its use in makeup formulations improves the texture and longevity of products on the skin.
Ink and Coating Solutions: Thanks to its solubility in most organic solvents, Copovidone serves as a binder in printing inks and coatings, contributing to the durability and gloss of printed materials. It ensures the even spread of ink and enhances the vibrancy of colors.
Adhesives: The polymer’s excellent adhesive properties and compatibility with plasticizers make it a choice ingredient in the production of industrial adhesives. Copovidone-based adhesives are valued for their strength and flexibility, suitable for various substrates.
Agricultural Films: Copovidone is used in agricultural films for its ability to form glossy, protective coatings. These films help in modifying the microclimate for crops, improving yield and protecting against pests.
03
Packages
The common packaging methods include:
Powder Form:
- Sealed in multi-layer polyethylene bags or aluminum foil bags to protect from moisture and contamination.
- These bags are often placed inside rigid, corrugated cardboard boxes or drums for additional protection during transport.
- Standard packaging sizes can range from 1 kg for small-scale use to 25 kg or more for industrial applications.
Aqueous Solutions:
- Packaged in high-density polyethylene (HDPE) bottles or drums, depending on the volume.
- For larger industrial quantities, intermediate bulk containers (IBC) made of plastic or stainless steel can be used.
- The containers are sealed and labeled with handling and safety instructions.
04
Specifications
Products | VP/VA Ration | K Value | Sulphated Ash(%,max.) | Residue NVP(%,max.) | Residue VA(%,max.) | Heavy Metals(ppm max.) |
VP/VA 64P | 60/40 | 26-34 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 64W | 60/40 | 26-34 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 73W | 70/30 | 26-34 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 37E | 30/70 | 24-32 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 55E | 50/50 | 30-38 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 64E | 60/40 | 26-34 | 0.1 | 0.03 | 0.01 | 20 |
VP/VA 73E | 70/30 | 30-38 | 0.1 | 0.03 | 0.01 | 20 |
05
Inquiry & Sample Request
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